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Upperton provides a flexible and dynamic approach to GMP manufacturing. From first-in-human (FIH) through to Phase III clinical supplies manufacturing at our MHRA and Home Office-approved (I-IV) GMP facility, Trent Gateway.

We offer manufacturing and packaging of Investigational Medicinal Products (IMP) in dosage forms including oral solid dosage forms, bulk dry powders, dry powder inhalers, nasal suspensions and solutions; for both biological molecules and small molecules.

  • Ten individual GMP manufacturing suites
  • Six high-potent processing rooms
  • Three non-contained processing rooms
  • Commercial-scale processing room

Our manufacturing process trains are built on the world’s leading technology, from a Gerteis Mini-Pactor to the O’Hara Tablet Coater, a GEA Post Hoist Blender, to the Zanasi Capsule Filler, and the Futorque X to ProCepT and Niro spray dryers.

Routes of delivery

  • Oral (solid, semi-solid and liquid forms)
  • Inhaled (nasal and pulmonary)
  • Parenteral (sterile fill/finish)

Dosage forms

  • Bulk spray-dried powders
  • Capsules
  • Tablets
  • Dry powder delivery devices (nasal and pulmonary)
  • Liquid delivery devices (nasal and pulmonary)