Since 1886, a high level of flexibility and an innovative spirit enables Dr Paul Lohmann庐 to respond to changing needs. Customers can profit from the broadest available portfolio of high-value minerals, with requirements of international pharmacopoeia, ensuring the highest quality for your applications.
Our strength lies in customised solutions tailored to your exact needs. We work closely with you to develop and optimise products, adjusting key parameters such as bulk density, wettability, particle size, purity and pH value to meet your specific requirements. This personalised approach, supported by our experienced R&D team, ensures that you receive the perfect solution for your application 鈥� giving you a distinct competitive advantage through innovation, reliability, and superior performance.
Active pharmaceutical ingredients (APIs) and excipients
In our GMP-certified production facilities, Dr Paul Lohmann produces around 100 APIs for various therapeutic areas, such as haematological, gastroenterological or cardiovascular applications according to international pharmacopoeia.
Since requirements for quality and documentation in the pharmaceutical industry are constantly increasing, Dr Paul Lohmann has established a Regulatory Affairs department of experts managing documentation of our products. We offer full regulatory and submission support for our GMP-approved mineral salts and provide numerous CEPs, ASMFs, DMFs and ASEAN-CTDs.
But the major component of ingredients in pharmaceutical products in terms of volume is not the active ingredient itself, it is the excipient. Therefore, we also offer mineral salts as excipients, which are of specific importance, since they largely determine the structure of solid dosage forms and stabilise the chemical properties in liquid pharmaceutical forms.
Salts for biopharma
Dr Paul Lohmann are experts in high-quality salt manufacturing and provide DPL-BioPharm Salts for upstream, downstream, and fill and finish processes of the biopharmaceutical industry. These salts act as nutrients for cell cultures, enzymatic co-factors as well as buffering agents within upstream processing and stabilisers of drug substances in final formulation.
For downstream processing, various mineral salts enable efficient bioprocesses for separation, precipitation and purification. Our multi-compendial DPL-BioPharm grade convinces with a constant and high quality including Bioburden (TAMY, TYMC) and heavy metal profile according to ICH Q3D.
Mineral salts low in endotoxins
Dr Paul Lohmann’s low-endotoxin mineral salts are specially produced in a dedicated facility, using strict protocols such as low-endotoxin process water, ensuring the highest quality. This allows us to provide customers with mineral salts that have a controlled LAL value, guaranteeing reliable processing. As a result, you benefit from increased production efficiency and output, while maintaining the safety and quality standards essential to your operations.
Low-endotoxin mineral compounds can be used in the following parenteral products:
- Solutions for injection
- Solutions for infusion
- Solutions for dialysis, peritoneal dialysis and haemofiltration
Directly compressible (DC) granules
DC granules by Dr Paul Lohmann have the right flowability, compressibility and particle size to be directly compressed into tablets without the need for additional processing steps, such as wet granulation. These processing properties contribute to health protection at work, reduces cost and optimises tablet manufacturing.
Triturations
As an additional service to customers who use trace elements in their applications 鈥� which are already toxic in small amounts 鈥� Dr Paul Lohmann offers these in the form of triturations with concentrations from 0.1% to 5%, diluted in inert carriers. To date, triturations of selenium, chromium, copper, molybdenum and iodine are available.
Direct blending, easy portioning, homogeneous mixtures, reduced toxicity and safe handling are obvious advantages. We can provide triturations in blended forms where required. This blending expertise can also be applied to tailor-made premixes of mineral salts and/or triturations.
Mineral salts 鈥� from your trusted partner
At our ISO and GMP-certified production sites in Germany, Dr Paul Lohmann uses state-of-the-art equipment and this, combined with our many years of extensive high-level manufacturing experience, ensures the highest and reliable quality.
Our commitment to supply chain stability, along with full transparency and traceability, ensures that you benefit from a dependable partnership. Let’s shape the future together and develop innovative solutions for your challenges.