On 7 August, artificial intelligence (AI)-powered digital health company Babylon Health with 94 staff to be laid off. The UK-based firm has faced a as losses have spiralled out of control.
The final blow to US operations was dealt when its planned merger with competitor MindMaze fell through. Once , the company has said it will focus on its home market, but even its future in the UK is uncertain.
Meanwhile, 11-year-old biopharma company has also announced a staff cut of 70% after the FDA rejected its experimental treatment for avasopasem, used to treat radiotherapy-induced severe oral mucositis, which causes difficulties in eating and drinking.
Curebase, a San Francisco-based digital clinical trials (DCT) start-up that was named in the top 6% of Y Combinator’s Top Private Companies list for 2023, has also announced layoffs amid a “refocus” that involves it scrapping its DCT business in favour of further developing its software offering.
The list goes on. Start-ups have high failure rates at the best of times, and even large medical companies often spend millions only for a lack of FDA approval or another regulatory hurdle to kill a product before it sees the light of day. The combination of the two leaves medical start-ups highly vulnerable.
Investors, too, are feeling less confident in the market. Venture capital funding for pharmaceutical companies by the beginning of August was 39% lower than the same time last year globally. Asia-Pacific, the second-largest market for funding, had a drop of 56.3%. This seeming lack of trust may indicate that the problems are deeper than just a few would-be unicorns going bust.
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