J&J hopes to supply more than one billion doses worldwide over the course of next year. Credit: pearson0612 from Pixabay.

(J&J) unit Janssen Pharmaceutical has signed an agreement with the US Government for the large scale domestic production and supply of 100 million doses of its Covid-19 vaccine candidate, Ad26.COV2.S.

The vaccine, based on Janssen AdVac technology, will be used in the US after it secures regulatory approval or emergency use authorisation.

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For this agreement, the US Biomedical Advanced Research and Development Authority (BARDA) and the Department of Defense have committed to providing more than $1bn.

The government may buy an additional 200 million doses of the vaccine in the future.

Johnson & Johnson chief scientific officer Paul Stoffels said: “Johnson & Johnson’s global team of experts has worked tirelessly alongside BARDA and scientific partners to pursue a SARS-CoV-2 vaccine that can help to stop the spread of Covid-19.

“We greatly appreciate the US government’s confidence in, and support for, our R&D platform and efforts and the scalability of our vaccine technology. We are scaling up production in the US and worldwide to deliver a SARS-CoV-2 vaccine for emergency use.”

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The company is developing the vaccine candidate as part of an ongoing research and development collaboration with BARDA. The product is currently in Phase I / IIa clinical trial in the US and Belgium.

If the vaccine is safe and effective, J&J hopes to supply more than one billion doses worldwide over the course of next year.

Last month, J&J said that the company is in discussions with the Government of Japan, as well as the Bill and Melinda Gates Foundation, regarding allocations of its Covid-19 vaccine candidate.

The US government already signed similar Covid-19 vaccine supply deals with Sanofi and GlaxoSmithKline (), as well as Pfizer and BioNTech.